Endocrine Abstracts

Ectopic thyroid tissue is the localization of thyroid tissue at any place other than the normal localization of the thyroid during the migration of embryonic period. Concurrent normal thyroid tissue may accompany. It usually is seen in women and in the midline. Very rarely thyroid carcinoma can develop. Treatment is like normal thyroid carcinomas, suggesting simultaneous thyroidectomy if accompanied by normal thyroid tissue. A 42-year-old female patient presented with complain...

Introduction: Determining the radiation dose to both the kidneys and malignant lesions from therapeutic administrations of Y-90 DOTATOC is critical for optimal management of neuroendocrine cancer patients. Here, a new dosimetric approach uses PET/CT to quantify the absolute activity of Y-90 immediately after administration to calibrate subsequent tissue clearance monitored with bremsstrahlung SPECT. The dosimetric information is used to personalize subsequent Y-90 DOTATOC dose...

Objective: Acromegaly is associated with increased cardiovascular morbidity and mortality. But the data about the evaluation of coagulation and fibrinolysis in acromegalic patients is very limited and to our knowledge, platelet function analysis has never been investigated. So we aimed to investigate the levels of protein C, protein S, fibrinogen, antithrombin 3, and platelet function analysis in patients with acromegaly.Methods: Thirty-nine patients wit...

Introduction and aim: The most endocrinologists in routine practice are used to Bethesda classification for evaluation of thyroid nodule in fine needle aspiration biopsy (FNA). It is accepted that FNA biopsy is an accurate diagnostic and gold standard test. However, false-positive diagnosis may sometimes occur as a patient with a ‘malign’ lesion is found incorrectly rather than an actually benign lesion on histological examination. Hashimoto’s thyroiditis probab...

Introduction: In this study, we aimed to compare GH values obtained in oral glucose tolerance test (OGTT) and intravenous glucose tolerance test (IVGTT) in healthy individuals.Material and methods: Data of 18 healthy volunteers were analysed (10 male and 8 female). Firstly all subjects were evaluated with 75 g oral glucose tolerance test. In another day, intravenous glucose tolerance test was performed. Serum glucose, insulin and GH levels obtained durin...

Objective: Thyroid fine-needle aspiration biopsy (FNAB) is the golden standard for approaching thyroid nodule’s malignancy. It is recommended to carry out an FNAB from the dominant nodule in multi nodular goiter. In our study, we compared the FNAB results that we carried out from dominant nodule and any other nodule which have features that may be malignant to US. Besides, the relationship between the results of cytology and US features of nodules has been analyzed.<p...

Objective: Hyperprolactinemia is the most common abnormality of the hypothalamic–pituitary axis. In the majority of patients with hyperprolactinemia monomeric prolactin (monoPRL) namely PRL with a molecular weight of 23 kDa predominates. But, in some patients with hyperprolactinemia high molecular weight forms of PRL namely macroprolactin (macroPRL) is detected. We aimed to investigate the clinic and radiologic features associated with the macroPRL....

Aim: The prevalence of overweight and obesity is increasing and becoming a global health problem. Obesity is the cause of increased cardiovascular morbidity and mortality and psychosocial problems. There are several reports which mentioning the unfavourable effects of aggressive weight loss regimes on the immune system. This study was designed to search for the effect of a straightforward, controlled and permanent weight loss program on the immune system.<p class="abstext"...

Diabetic foot is one of the most feared complication of diabetes. The tendons and ligaments’ stiffness and elasticity are known to be altered in diabetic foot. Achilles tendon (AT) plays an important for foot biomechanics and the altered stiffness of AT may have a role in pathogenesis of diabetic foot. Determination of the early changes in AT may help to identify the risky patients for diabetic foot. Acoustic Radiation Force Impulse (ARFI) Elastography is an elastography ...

Introduction: Recent studies showed that post-menopausal osteoporosis and weight gain starts at the perimenopause stage, a period characterized by relatively stable estrogen and rising FSH levels. FSH is found to be associated with adiposity in women, which is also a great risk factor for type 2 DM. There is also a sharp increase in visceral adiposity during this life stage, which coincides with the emergence of disrupted energy balance and reduced physical activity. There is ...